Aggregation of Therapeutic Proteins
Understanding and controlling protein aggregation The growth of therapeutic proteins as candidates in drug development pipelines is progressing at a record speed, outpacing significantly small-molecule drug development. Development of commercial protein drugs has been hampered by a variety of sources for instability, particularly the high tendency of protein molecules to aggregate under a wide range of processing and storage conditions. Aggregation of Therapeutic Proteins provides pharmaceutical scientists with a much-needed overview of the causes, consequences, characterization, and control of the aggregation of therapeutic proteins. Aggrega…
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Produktdetails
Weitere Autoren: Roberts, Christopher J. (Hrsg.)
- ISBN: 978-0-470-76981-2
- EAN: 9780470769812
- Produktnummer: 13906805
- Verlag: Wiley
- Sprache: Englisch
- Erscheinungsjahr: 2010
- Seitenangabe: 484 S.
- Plattform: PDF
- Masse: 5'820 KB
Über den Autor
WEI WANG, PhD, is a Research Fellow at Pfizer Global Biologics. He is also Adjunct Professor in the School of Pharmacy and Health at the University of the Pacific in California and Guest Professor at Shandong University in China. CHRISTOPHER J. ROBERTS, PhD, is Associate Professor of Chemical Engineering at the University of Delaware. Previously, he was a senior research scientist in pharmaceutical R & D at Pfizer.
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