Handbook of Histology Methods for Bone and Cartilage

Histologists and histochemists must spend considerable effort today to find the methods essential to perform bone and cartilage-related research. In Handbook of Histology Methods for Bone and Cartilage, Y.H. An and K.L. Martin have assembled an extensive collection of the major methods for studying the histology and histomorphometry of bone and cartilage. Described by well-experienced researchers, physicians, and technicians, the methods include techniques for bone labeling, bone sectioning, histological analysis, histomorphometric analysis, radiological examination, and contact radiography. Among the applications presented are in situ hybridization of bone and cartilage, radiological examination of calcified tissue with emphasis on bone, and dealing with histology artifacts in hard-tissue research. There are also histological techniques for the analysis of bone-implant interfaces, cartilage-defect repair, and the soft-tissue biomaterial interface. More practical than theoretical, the text is simple and straightforward, with many tables, line drawings, and micro- and macro photographs to illustrate the content. Full bibliographies at the end of each chapter guide the reader to additional detailed information. Comprehensive and up-to-date, the Handbook of Histology Methods for Bone and Cartilage offers researchers a practical guide to all the major histological and histomorphometrical methods of bone and cartilage analysis-a gold mine of detailed techniques for the preparation of tissue from collection through fixation, embedding, sectioning, and staining.